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1. Genesis Software Solutions Inc
2. Genesis Software Program
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GENESIS (The General Neural Simulation System) is a simulation environment for constructing realistic models of neurobiological systems at many levels of scale including: sub-cellular processes, individual neurons, networks of neurons, and neuronal systems. These simulations are “computer-based implementations of models whose primary objective is to capture what is known of the anatomical structure and physiological characteristics of the neural system of interest”.^[4] GENESIS is intended to quantify the physical framework of the nervous system in a way that allows for easy understanding of the physical structure of the nerves in question. “At present only GENESIS allows parallelized modeling of single neurons and networks on multiple-instruction-multiple-data parallel computers.”^[5] Development of GENESIS software spread from its home at Caltech to labs at the University of Texas at San Antonio, the University of Antwerp, the National Centre for Biological Sciences in Bangalore, the University of Colorado, the Pittsburgh Supercomputing Center, the San Diego Supercomputer Center, and Emory University.

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Neurons and Neural Systems[edit]

GENESIS works by creating simulation environments for constructing models of neurons or neural systems. 'Nerve cells are capable of communicating with each other in such a highly structured manner as to form neuronal networks. To understand neural networks, it is necessary to understand the ways in which one neuron communicates with another through synaptic connections and the process called synaptic transmission'.^[6] Neurons have a specialized structure for their function, they 'are different from most other cells in the body in that they are polarized and have distinct morphological regions, each with specific functions'.^[6] The two important regions of a neuron are the dendrite and the axon. 'Dendrites are the region where one neuron receives connections from other neurons. The cell body or soma contains the nucleus and the other organelles necessary for cellular function. The axon is a key component of nerve cells over which information is transmitted from one part of the neuron (e.g., the cell body) to the terminal regions of the neuron'.^[6] The third important piece of a neuron is the synapse. 'The synapse is the terminal region of the axon this is where one neuron forms a connection with another and conveys information through the process of synaptic transmission'.^[6]

Neural networks like the ones simulated with GENESIS software can quickly become highly complex and difficult to understand. 'Just a few interconnected neurons (a microcircuit) can perform sophisticated tasks such as mediate reflexes, process sensory information, generate locomotion and mediate learning and memory. Even more complex networks, macrocircuits, consist of multiple embedded microcircuits. Macrocircuits mediate higher brain functions such as object recognition and cognition'.^[6] GENESIS endeavors to simulate neural systems as they are found in nature. Often, 'a neuron can receive contacts from up to 10,000 presynaptic neurons, and, in turn, any one neuron can contact up to 10,000 postsynaptic neurons. The combinatorial possibility could give rise to enormously complex neuronal circuits or network topologies, which might be very difficult to understand'.^[6]

History[edit]

GENESIS was developed by Dr. James M. Bower, in the Caltech laboratory, and first released to the public in 1988 in association with the first Methods in Computational Neuroscience Course at the Marine Biological Laboratory in Woods Hole, MA. Full source code for the software was released in the same year under an open software model for development. It's now supported by the Computational Biology Initiative at the University of Texas at San Antonio and is available free along with tutorial guides on its use.P-GENESIS, a parallel version of GENESIS, was first run in 1990 on the Intel Delta, which was the prototype for the Intel Paragon family of massively parallel supercomputers.

How GENESIS Works[edit]

GENESIS is useful in creating a simulation environment for constructing models of neurobiological systems such as:

The GENESIS system is complicated, but relatively easy to use.

An individual can input commands through one of three ways: script files, graphical user interface, or the GENESIS command shell. These commands are then processed by the script language interpreter. 'The Script Language Interpreter processes commands entered through the keyboard, script files, or the graphical user interface, and passes them to the GENESIS simulation engine. The simulation engine also loads compiled object libraries, reads and writes data files, and interacts with the graphical user interface'.^[7] Below is a graphical representation of the user input process and a sample GENESIS output.

Applications[edit]

Most current applications for GENESIS involve realistic simulations of biological systems. It is usually used to simulate the behavior of larger brain structures, for example the cerebral cortex. These studies most often occur in lab courses in neural simulation at Caltech and the Marine Biological Laboratory at Woods Hole, Massachusetts.

GENESIS can be used in combination with Yale University’s software called NEURON as a means for scientists to collaborate to construct a physical description of the nervous system. The GENESIS software can also be used with Kinetikit in the modeling of signal transduction pathways.^[8]

GENESIS has been used in many studies.^[9] Some of these studies involve research that focuses on the development of software that would be useful across many disciplines. Others are studies of neurons, such as Purkinje cells. These studies used GENESIS to simulate Purkinje cells and could be useful for the planning and development of later experiments using the GENESIS software.

There may also be biomedical applications of the software. For example, St. Jude Medical in Europe has developed an implanted GENESIS device.^[10]

See also[edit]

Publications[edit]

• The Book of GENESIS: Exploring Realistic Neural Models with the GEneral NEural SImulation System, Springer, (1998), ISBN978-0-387-94938-3

References[edit]

1. ^ ^ab'The GENESIS 2 simulator home page'. GENESIS project. Retrieved 26 December 2015.
2. ^ ^ab'Platforms'. GENESIS project. Retrieved 1 October 2016.
3. ^'The Ultimate GENESIS 2.3 CDROM Distribution'. GENESIS project. Retrieved 26 December 2015.
4. ^(Bower, Beeman, and Hucka. GENESIS Simulation Software. 1998)
5. ^(A consumer guide to neuronal modeling software TRENDS IN NEUROSCIENCES 15: 462-464, 1992 Copyright © Elsevier Science Publishers Ltd, (UK), 1992 E. De Schutter Division of Biology 216-76, California Institute of Technology, Pasadena, CA 91125, USA)
6. ^ ^abcdef(Introduction to Neurons and Neuronal Networks John H. Byrne, Ph.D., Department of Neurobiology and Anatomy, The UT Medical School at Houston)
7. ^(Bower, Beeman, and Hucka. GENESIS Simulation Software. 1998.)
8. ^(Bhalla, U.S. (2002).Use of Kinetikit and GENESIS for modeling signaling pathways. In: Methods in Enzymology, ed. Hildebrandt, J.D and Iyengar, R. Academic Press, 345, 3-23.)
9. ^GENESIS Publications
10. ^Video: GENESIS Implanted Device

External links[edit]

Genesys, (also known as Genesys Telecommunications Laboratories, Inc.), is a company that sells customer experience and call center technology to mid-sized and large businesses.^[4] It sells both cloud-based and on-premises software. Genesys is headquartered in Daly City, California,^[4] and has offices in Canada, Latin America, Europe, the Middle East, Africa, Asia, and Australia. The company was founded in 1990^[5] and was most recently acquired by Permira Funds and Technology Crossover Ventures in February 2012.^[6]

Genesis Software Solutions Inc

• 1History

History[edit]

Genesis Software Program

Founding and ownership[edit]

Genesys was founded by Gregory Shenkkman and Alec Miloslavsky in October 1990.^[5][7] The company's original seed funding was $150,000 in loans from the founders' families.^[5] The company completed its initial public offering (IPO) in June 1997 and was listed on the NASDAQstock exchange under the ticker symbol GCTI. Paul Segre succeeded Wes Hayden as Genesys's chief executive officer (CEO) in October 2007.^[8]Tony Bates joined Genesys as the new CEO in May 2019.

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Alcatel-Lucent (then Alcatel) acquired Genesys for $1.5 billion in late 1999.^[9]

Permira and Technology Crossover Ventures acquired Genesys from Alcatel-Lucent for $1.5 billion in February 2012 ^[6][10]

Acquisitions[edit]

1997 Forte Software, Inc. (later renamed Adante), a developer of e-mail management software, in December 1997,^[11] and Next Age Technologies, a workforce management software developer.^[12]

2001 IBM's CallPath computer telephony integration (CTI) assets .^[13]

2002 Telera, a Campbell, California-based developer of voice portal and interactive voice response (IVR) systems f ^[14]

2007 Informiam, a developer of performance management software for customer service operations.^[16]

2008 Conseros, developer of high-volume work item management software^[17] and SDE Software Development Engineering, a creator of hosting management software.^[18]

2014 Solariat (March 2014) for social media analytics.^[26]

2014 OVM Solutions (May 2014) for cloud-based proactive communications and customer interactions.^[27]

2016 EIT regional partner in Korea - acquiring the Genesys division in November 2016.^[30]

2017 The company also acquired Silver Lining in February 2017 for Employee Performance Management, providing applications to support and analyze employee performance and learning automation.^[32]

Genesis Software Company Inc

References[edit]

1. ^'Leadership'. Genesys.com.
2. ^'Genesys to Acquire Interactive Intelligence to Create the World's Premier Omnichannel Customer Experience Company'. Business Wire. 31 August 2016.
3. ^Genesys LinkedIn
4. ^ ^abPatrick Hoge (11 March 2014). 'To go, or not to go: Tech's IPO shuffle'. San Francisco Business Times. Retrieved 6 May 2014.
5. ^ ^abcScott McCormack (6 July 1998). 'The Russia house'. Forbes. Retrieved 6 May 2014.
6. ^ ^abPatrick Hoge (15 June 2012). 'Paul Segre, president and CEO of Genesys'. San Francisco Business Times. Retrieved 6 May 2014.
7. ^'Genesys Telecommunications Laboratories, Inc'. Securities and Exchange Commission. 1997. Retrieved 7 May 2014.
8. ^Leonard Klie (3 October 2007). 'Genesys CEO Leaves for Nuance Post'. Destination CRM. Retrieved 7 May 2014.
9. ^'Alcatel plans to buy Genesys for $1.5 Billion'. The New York Times. 29 September 1999. Retrieved 7 May 2014.
10. ^'Alcatel-Lucent sells Genesys for $1.5bn'. Financial Times. 19 October 2011. Retrieved 7 May 2014.
11. ^'Finance: Call Center House Forte is now Adante after Acquisition'. Network Briefing. 24 March 1998.
12. ^'Form 10-K'. Securities and Exchange Commission. Retrieved 7 May 2014.
13. ^'Genesys' Acquisition of IBM's CallPath Will Allow Both to Focus'. May 16, 2001.
14. ^Ann Bednarz (5 August 2002). 'Genesys delivers self-service voice app Alcatel subsidiary joins call center rivals in adding VoiceXML support'. Network World.